C-peptide is a component of the secretion of the endocrine pancreas, which is an indicator of insulin production and is used to diagnose diabetes mellitus (DM), drawing up his prediction and monitoring his treatment, as well as for the diagnosis of certain pancreatic tumors.

The C-peptide analysis provides information even with the administration of exogenous insulin and in the presence of antibodies to insulin - in contrast to the analysis for Insulin. This is of great importance in the examination of patients with diabetes mellitus of the first type. The C-peptide analysis allows to evaluate the correctness of the selected insulin therapy regimen - if there is a shortage of insulin, the C-peptide readings will be significantly reduced.

The analysis for C-peptide is prescribed in several cases: if it is necessary to differentiate the first and second diabetes mellitus, to determine the correctness of insulin therapy, if insulin is suspected, to monitor the state of the body in liver diseases and after removal of the pancreas.

It is recommended to donate blood in the morning (from 8 to 11 o'clock), on an empty stomach (at least 8 and not more than 14 hours of fasting, you can drink water). On the eve avoid food overload. One day prior to blood collection, it is necessary to exclude alcohol intake, 1 hour before blood collection - smoking.

Elevated levels of C-peptide will be observed with non-insulin-dependent diabetes mellitus, renal failure, taking hormonal drugs (including hormonal contraceptives), insulin, and hypertrophy of beta cells. A low content of c-peptide is characteristic of insulin-dependent diabetes mellitus, with hypoglycemia (including alcohol), under stress.